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Dr. Matthias F. J. Sperl

Dr. Matthias Sperl

Dr. Sperl is a psychological psychotherapist for cognitive behavioral therapy and works as a Senior Lecturer within the professorship for Clinical Psychology and Psychotherapy. His research focuses on the mechanisms of anxiety and fear. His research interests include:

  • Pathological fear and anxiety
  • Imagery in fear conditioning
  • Simultaneous EEG-fMRI integration
  • Noradrenergic mechanisms of fear-related processes
  • Expectation violations in fear extinction
  • Personality traits and fear conditioning/extinction

Postal address:
University of Siegen
Faculty II - Department of Psychologie
Clinical Psychology and Psychotherapy
Obergraben 23
D-57072 Siegen

ACADEMIC CAREER

INTERNATIONAL RESEARCH EXPERIENCE

PSYCHOTHERAPEUTIC QUALIFICATION

  • 2018 – 2024    Postgraduate Training as a Psychological Psychotherapist (Cognitive Behavioral Therapy)
    University of Giessen, State licensing examination, approbation (very good)
  • 2019 – 2024    Outpatient clinical work at the University of Giessen, Department of Psychology, Behavioral Therapy Clinic
    as part of postgraduate training in cognitive behavioral psychotherapy
  • 2018 – 2019    Inpatient clinical work at the University Hospital of Giessen and Marburg, Center for Psychiatry and Psychotherapy Giessen
    as part of postgraduate training in cognitive behavioral psychotherapy

PULICATIONS

Weinreich, L., Moll, K., Sperl, M. F. J., Schulte-Körne, G., & Timmermans, B. (in press). Experimental investigations of social exclusion among adolescents with psychiatric disorders: A systematic review. European Child & Adolescent Psychiatry.
https://doi.org/10.1007/s00787-025-02687-9

Hartmann, H.*, Gürsoy, Ç.*, Lischke, A., Mueckstein, M., Sperl, M. F. J., Vogel, S., Yang, Y.-F., Feld, G. B., Kastrinogiannis, A.*, & Koppold, A.* (2025). ARIADNE – a scientific navigator to find your way through the resource labyrinth. Advances in Methods and Practices in Psychological Science, 8, 1–20.
https://doi.org/10.1177/25152459241297674
* Shared first/senior authorships

Röseler, L., Kaiser, L., Doetsch, C., Klett, N., Seida, C., Schütz, A., Aczel, B., Adelina, N., Agostini, V., Alarie, S., Albayrak-Aydemir, N., Aldoh, A., Al-Hoorie, A. H., Azevedo, F., Baker, B. J., Barth, C. L., Beitner, J., Brick, C., Brohmer, H., Chandrashekar, S. P., Chung, K. L., Cockcroft, J. P., Cummins, J., Diveica, V., Dumbalska, T., Efendic, E., Elsherif, M., Evans, T., Feldman, G., Fillon, A., Förster, N., Frese, J., Genschow, O., Giannouli, V., Gjoneska, B., Gnambs, T., Gourdon-Kanhukamwe, A., Graham, C. J., Hartmann, H., Haviva, C., Herderich, A., Hilbert, L. P., Holgado, D., Hussey, I., Ilchovska, Z. G., Kalandadze, T., Karhulahti, V.-M., Kasseckert, L., Klingelhöfer-Jens, M., Koppold, A., Korbmacher, M., Kulke, L., Kuper, N., LaPlume, A., Leech, G., Lohkamp, F., Lou, N. M., Lynott, D., Maier, M., Montefinese, M., Meier, M., Moreau, D., Mrkva, K., Nemcova, M., Oomen, D., Packheiser, J., Pandey, S., Papenmeier, F., Paruzel-Czachura, M., Pavlov, Y. G., Pavlović, Z., Pennington, C. R., Pittelkow, M.-M., Plomp, W., Plonski, P. E., Pronizius, E., Pua, A. A., Pypno, K., Rausch, M., Rebholz, T. R., Richert, E., Röer, J. P., Ross, R., Schmidt, K., Skvortsova, A., Sperl, M. F. J., Tan, A. W. M., Thürmer, J. L., Tołopiło, A., Vanpaemel, W., Vaughn, L. A., Verheyen, S., Wallrich, L., Weber, L., Wolska, J. K., Zaneva, M., & Zhang, Y. (2024). The Replication Database: Documenting the replicability of psychological science. Journal of Open Psychology Data, 12, 8.
https://doi.org/10.5334/jopd.101 

Schiller, B., Sperl, M. F. J., Kleinert, T., Nash, K., & Gianotti, L. (2023). EEG microstates in social and affective neuroscience. Brain Topography, 37, 479–495.
https://doi.org/10.1007/s10548-023-00987-4

Schenkel, S.*, Emmerich, L.*, Arzapalo, H., Danböck, S. K., Dietiker, L., El-Haj-Mohamad, R., Meyer, C., Sperl, M. F. J., von Wendorff, C., Wallimann, M., Windthorst, P., Glaesmer, H. & Schäfer, I. (2023). Selbst- und Fremdaggression bei Frauen mit Posttraumatischer Belastungsstörung und substanzbezogenen Störungen. Welche Rolle spielen Emotionsregulationsstrategien? Trauma & Gewalt, 17, 296–311.
https://doi.org/10.21706/tg-17-4-296
* Shared first authorship

Nebe, S.*, Reutter, M.*, Baker, D. H., Bölte, J., Domes, G., Gamer, M., Gärtner, A., Gießing, C., Gurr, C., Hilger, K., Jawinski, P., Kulke, L., Lischke, A., Markett, S., Meier, M., Merz, C. J., Popov, T., Puhlmann, L. M. C., Quintana, D. S., Schäfer, T., Schubert, A.-L., Sperl, M. F. J., Vehlen, A., Lonsdorf, T. B.*, & Feld, G.* (2023). Enhancing precision in human neuroscience. eLife, 12, 85980.
https://doi.org/10.7554/eLife.85980
* Shared first/senior authorships

Sperl, M. F. J., Panitz, C., Skoluda, N., Nater, U. M., Pizzagalli, D. A., Hermann, C., & Mueller, E. M. (2022). Alpha-2 adrenoreceptor antagonist yohimbine potentiates consolidation of conditioned fear. International Journal of Neuropsychopharmacology, 25, 759–773.
https://doi.org/10.1093/ijnp/pyac038
Open Data and Open Material available online at zenodo
https://doi.org/10.5281/zenodo.6833565

Rief, W.*, Sperl, M. F. J.*, Braun-Koch, K., Khosrowtaj, Z., Kirchner, L., Schäfer, L., Schwarting, R. K. W., Teige-Mocigemba, S., & Panitz, C. (2022). Using expectation violation models to improve outcome of psychological treatments. Clinical Psychology Review, 98, 102212.
https://doi.org/10.1016/j.cpr.2022.102212
* Shared first authorship

Lonsdorf, T. B., Hartwigsen, G., Kübler, A., Merz, C. J., Schmidt, B., Sperl, M. F. J., & Feld, G. B. (2022). Mehr als nur fragwürdig: Reproduzierbarkeit und Open Science in der Lehre aus Sicht der Biologischen Psychologie und Neuropsychologie. Psychologische Rundschau, 73, 30–33.
https://doi.org/10.1026/0033-3042/a000569

Panitz, C., Endres, D., Buchholz, M., Khosrowtaj, Z., Sperl, M. F. J., Mueller, E. M., Schubö, A., Schütz, A. C., Teige-Mocigemba, S., & Pinquart, M. (2021). A revised framework for the investigation of expectation update versus maintenance in the context of expectation violations: The ViolEx 2.0 model. Frontiers in Psychology, 12, 726432.
https://doi.org/10.3389/fpsyg.2021.726432

Göhler, A. C., Haas, J. W., Sperl, M. F. J., Hermann, C., & Winkler, A. (2021): Placebo nasal spray protects female participants from experimentally induced sadness and concomitant changes in autonomic arousal. Journal of Affective Disorders, 295, 131–138.
https://doi.org/10.1016/j.jad.2021.07.037
Open Data and Open Material available online at zenodo
https://doi.org/10.5281/zenodo.5162847

Bierwirth, P., Sperl, M. F. J., Antov, M. I., & Stockhorst, U. (2021). Prefrontal theta oscillations are modulated by estradiol-status during fear recall and extinction recall. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 6, 1071–1080.
https://doi.org/10.1016/j.bpsc.2021.02.011

Sperl, M. F. J., Wroblewski, A., Mueller, M., Straube, B., & Mueller, E. M. (2021). Learning dynamics of electrophysiological brain signals during human fear conditioning. NeuroImage, 226, 117569.
https://doi.org/10.1016/j.neuroimage.2020.117569
Open Data and Open Material available online at zenodo
https://doi.org/10.5281/zenodo.4294603

Mueller, E. M., Sperl, M. F. J., & Panitz, C. (2019). Aversive imagery causes de novo fear conditioning. Psychological Science, 30, 1001–1015.
https://doi.org/10.1177/0956797619842261
Open Data and Open Material available online at zenodo
https://doi.org/10.5281/zenodo.2591593

Sperl, M. F. J., Panitz, C., Rosso, I. M., Dillon, D. G., Kumar, P., Hermann, A., Whitton, A. E., Hermann, C., Pizzagalli, D. A., & Mueller, E. M. (2019). Fear extinction recall modulates human frontomedial theta and amygdala activity. Cerebral Cortex, 29, 701–715.
https://doi.org/10.1093/cercor/bhx353

Panitz, C., Sperl, M. F. J., Hennig, J., Klucken, T., Hermann, C., & Mueller, E. M. (2018). Fearfulness, neuroticism/anxiety, and COMT Val158Met in long-term fear conditioning and extinction. Neurobiology of Learning and Memory, 155, 7–20.
https://doi.org/10.1016/j.nlm.2018.06.001

Sperl, M. F. J., Panitz, C., Hermann, C., & Mueller, E. M. (2016). A pragmatic comparison of noise burst and electric shock US for fear conditioning research with many trials. Psychophysiology, 53, 1352–1365.
https://doi.org/10.1111/psyp.12677

BOOK CHAPTERS

Hermann, C., & Sperl, M. F. J. (2023). Classical Conditioning. In J. L. Matson (Ed.), Handbook of Clinical Child Psychology: Integrating Theory and Research into Practice (pp. 425–457). Springer. https://doi.org/10.1007/978-3-031-24926-6_21 (Free-access link: https://rdcu.be/dfqGS)

SCIENCE COMMUNICATION AND MEDIA COVERAGE

TV-Beitrag bei WDR Lokalzeit Südwestfalen (27. Januar 2025). Vor fünf Jahren erster Corona-Verdachtsfall in Südwestfalen (ab Min. 17:40: Filmbeitrag von Julia Arns, ab Min. 21:00: Live-Studiogespräch über psychische Folgen der Corona-Pandemie mit Dr. Matthias Sperl).
https://www1.wdr.de/lokalzeit/fernsehen/suedwestfalen/lokalzeit-suedwestfalen-clip-lokalzeit-suedwestfalen--27-01-2025-100.html

Museum für Gegenwartskunst MGK Siegen (23. Januar 2025). Psychologische Kunstführung „Eintauchen in die Blicke“, Dialogführung mit Psychotherapeut Dr. Matthias Sperl und Kuratorin Jessica Schiefer.
https://www.mgksiegen.de/de/kalender/7352/eintauchen-in-die-blicke

Live-Interview bei Radio Siegen mit Dr. Matthias Sperl (06. September 2024). Nosferatu-Spinne – Warum haben wir Angst vor ihr?
https://www.radiosiegen.de/artikel/nosferatu-spinne-warum-haben-wir-angst-vor-ihr-2096576.html

Wortlaut-Zeitungsinterview mit Dr. Matthias Sperl (17. August 2024). Angst – woher sie kommt, was sie mit uns macht.
Erschienen auf Seite 3 in allen Tageszeitungen von VRM Medien:
Allgemeine Zeitung (Mainz – Rheinhessen; Alzey; Rheinhessen – Nahe), Wiesbadener Kurier (Wiesbaden – Stadt; Rheingau; Untertaunus – Idsteiner Land), Bürstädter Zeitung, Lampertheimer Zeitung, Main-Spitze, Wormser Zeitung, Darmstädter Echo, Groß-Gerauer Echo, Odenwälder Echo, Rüsselsheimer Echo, Starkenburger Echo, Dill-Zeitung, Herborner Tageblatt, Hinterländer Anzeiger, Wetzlarer Neue Zeitung, Weilburger Tageblatt, Nassauische Neue Presse, Hochheimer Zeitung.
https://www.allgemeine-zeitung.de/panorama/wissenschaft/angst-woher-sie-kommt-was-sie-mit-uns-macht-3887109
Kostenfreier Zugang über OPUS der Universität Siegen: http://dx.doi.org/10.25819/ubsi/10560

Forschung und Lehre (05. August 2024). Wie Angst und Furcht im Gehirn entstehen.
https://www.forschung-und-lehre.de/forschung/wie-angst-und-furcht-im-gehirn-entstehen-6571

Rhein-Zeitung (05. August 2024). Angstforschung an der Uni Siegen: Psychotherapeut mit Nachwuchspreis ausgezeichnet.
Erschienen auf Seite 20 in der Rhein-Zeitung (Kreis Altenkirchen).
https://www.rhein-zeitung.de/region/aus-den-lokalredaktionen/kreis-altenkirchen_artikel,-angstforschung-an-der-uni-siegen-psychotherapeut-mit-nachwuchspreis-ausgezeichnet-_arid,2679499.html

Westfalenpost (04.August 2024). Siegen: Psychologe arbeitet an Bremspedal für Panikattacken.
Erschienen auf Seite 3 in der Westfalenpost (Zeitung für das Siegerland).
https://www.wp.de/lokales/siegen-und-umland/article406943931/siegen-psychologe-arbeitet-an-bremspedal-fuer-panikattacken.html

Medizin Aspekte (02. August 2024). Angststörungen besser behandeln – neue Therapien.
https://medizin-aspekte.de/angststoerungen-besser-behandeln-neue-therapien-150509

Informationsdienst Wissenschaft IDW (01. August 2024). Neue Erkenntnisse und Therapieansätze: So entstehen Angst und Furcht im Gehirn.
https://nachrichten.idw-online.de/2024/08/01/neue-erkenntnisse-und-therapieansaetze-so-entstehen-angst-und-furcht-im-gehirn

Press release from the University of Siegen (August 01, 2024). How do fear and anxiety arise in the brain?
https://www.uni-siegen.de/start/news/forschungsnews/1039442.html

TV report at WDR Lokalzeit Südwestfalen (July 12, 2024). Living with an anxiety disorder (from min. 07:00: film clip by Elisabeth Konstantinidis, from min. 11:30: Live studio talk about anxiety disorders and psychotherapy with Dr. Matthias Sperl).
https://www1.wdr.de/lokalzeit/fernsehen/suedwestfalen/lokalzeit-suedwestfalen-clip-lokalzeit-suedwestfalen--12-07-2024-100.html

Sperl, M. F. J. (2023). Eine schreckliche Erinnerung: Was ist damals (in meinem Gehirn) passiert? SciLogs, KarText Blog der Klaus Tschira Stiftung (Spektrum der Wissenschaft, Heidelberg).
https://scilogs.spektrum.de/klartext/eine-schreckliche-erinnerung

AWARDS

  • 2025    Teaching Award “Best Teaching in the Winter Semester 2024/25”
    awarded by the Student Council of Psychology at the University of Siegen
  • 2025    Teaching Award “Best Engagement in the Winter Semester 2024/25”
    awarded by the Student Council of Psychology at the University of Siegen
  • 2024    Early Career Award of the German Society for Psychophysiology and its Application (DGPA)
    awarded for a research contribution in the field of psychophysiology, consisting of four publications (first authorships) from the past five years
  • 2023    Dissertation Award (2nd Prize), German Psychological Society (DGPs), Section for General and Experimental Psychology
    for the dissertation https://doi.org/10.17192/z2021.0500
    (selected from dissertations that were completed between November 2020 and October 2022)
  • 2019    Poster Award, Research Training Group 2271 (University of Marburg), Hirschegg Retreat (Austria)
    for a poster on learning dynamics of electrophysiological brain signals during human fear conditioning
  • 2018    Brain Products Young Scientist Award for a Distinguished Contribution in EEG Research
    awarded by the German Society for Psychophysiology and its Application (DGPA) and Brain Products (Munich), for the Cerebral Cortex paper  on EEG-fMRI coupling in fear extinction
  • 2017    Poster Award, Society for Psychophysiological Research (SPR), Annual Meeting Vienna (Austria)
    for a poster on noradrenergic mechanisms of fear conditioning
  • 2017    Young Researcher Award of the World Association for Stress Related and Anxiety Disorders (WASAD)
    for the Cerebral Cortex paper  on EEG-fMRI coupling in fear extinction

SCHOLARSHIPS AND FUNDING

  • 2023    Elfriede Dietrich Foundation
    "Elfriede Dietrich Research Award" funding for a research project on memory processes in Posttraumatic Stress Disorders, in collaboration with Dr. Laura Nohr (Freie Universität Berlin), Rayan El-Haj-Mohamad (Freie Universität Berlin), and Lina Krakau (University Medical Center of the Johannes Gutenberg University Mainz)
  • 2022    German Speaking Society for Psychotraumatology (DeGPT)
    Scholarship for the DeGPT Summer School in the Villa Garbald (Castasegna, Schweiz), contribution: "Hyperconsolidation of traumatic experiences: Alpha-2 Adrenoreceptor Antagonist Yohimbine facilitates consolidation of conditioned fear"
  • 2020    Research Training Group 2271, University of Marburg
    "Treasure Box Award", funding for a research project on expectation violations in fear extinction in collaboration with Karoline Körfer (University of Marburg)
  • 2019    Society for Psychophysiological Research (SPR)
    Research Travel Award, Annual Meeting Washington/DC (USA)
  • 2018    Society for Psychophysiological Research (SPR)
    Research Training Fellowship for a six-month research visit at McLean Hospital / Harvard Medical School, Boston/MA (USA)
  • 2016    German Academic Exchange Service (DAAD)
    Marburg International Doctorate Travel Award, Annual Meeting of the Society for Psychophysiological Research (SPR), Minneapolis/MN (USA)
  • 2016    German Psychological Society (DGPs), Section for Personality Psychology and Psychological Diagnostics
    Scholarship for a PhD students workshop, Landau/Pfalz, contribution: "Neurobiological mechanisms of personality differences in fear extinction"
  • 2015 – 2016    German Academic Exchange Service (DAAD)
    PROMOS Scholarship for a six-month research visit at McLean Hospital / Harvard Medical School, Boston/MA (USA)
  • 2015    Society for Psychophysiological Research (SPR)
    International Travel Award, Annual Meeting Seattle/WA (USA)

INVOLVEMENT IN PROFESSIONAL SOCIETIES

REVIEWER ACTIVITY

Behaviour Research and Therapy (Member of the Associate Editorial Board ); Biological Psychiatry: Cognitive Neuroscience and Neuroimaging; Biological Psychiatry: Global Open Science; Biological Psychology; Brain Structure and Function; Cerebral Cortex; Clinical Psychology in Europe; Cognition and Emotion; Cognitive, Affective, and Behavioral Neuroscience; Cognitive Processing; European Journal of Neuroscience; Experimental Psychology; Frontiers in Neuroscience; Frontiers in Psychiatry; Human Brain Mapping; International Journal of Psychophysiology; iScience; Journal of Affective Disorders; Journal of Behavioral Addictions; Journal of Cognitive Psychology; Journal of Consumer Behaviour; Learning & Memory; NeuroImage; NeuroImage: Clinical; Neuropsychologia; PLOS Biology; PLOS ONE; Psychiatry Research: Neuroimaging; Psychoneuroendocrinology; Psychopharmacology; Psychophysiology; Social Cognitive and Affective Neuroscience; Social Neuroscience; Scientific Reports; Stress; Zeitschrift für Psychologie

Aktualisiert via XIMS am 23.4.2025 von E. Reinhardt
 
 
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